If you're in serious need of a running back then go for it. I just don't see him being a big difference maker in fantasy with that OL. I also don't see him getting near the same volume as Barkley did, even though his role will obviously expand.
my RB's are rough this year. I have the 3rd waiver pickup and i'm in a 14 team league so odds of me landing him are slim. I hope I can get him to help me for a few weeks until Melvin Gordon decides to lace up.